Risk factors for the bipolar and depression spectra

被引：92

作者：

Angst, J ^{[1
]}

Gamma, A ^{[1
]}

Endrass, J ^{[1
]}

机构：

[1] Psychiat Univ Hosp, CH-8029 Zurich, Switzerland

来源：

ACTA PSYCHIATRICA SCANDINAVICA | 2003年 / 108卷

关键词：

bipolar disorder; depression; mood lability; risk factor; vulnerability;

D O I：

10.1034/j.1600-0447.108.s418.4.x

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective: To identify risk factors for mood disorders in a community sample studied from the ages of 20 to 35 years. Method: Social characteristics, a family history of mood disorders and some personality features were analysed as risk factors for bipolar and depressive disorders by means of logistic regression. Results: Frequent 'ups and downs' of mood were the strongest risk factor for both bipolar and depressive disorders; a weaker risk factor for both was emotional/vegetative lability (neuroticism). An additional risk factor for bipolar disorders was a positive family history of mania, whereas for depression it was a positive family history of depression/fatigue. As a risk factor for bipolar disorders, 'ups and downs' were much stronger than a positive family history of mania. Frequent ups and downs were independent of the family history of mood disorders. Conclusion: The results suggest that mood regulation should be investigated as a new, very important independent risk factor for mood disorders.

引用

页码：15 / 19

页数：5

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