Specificity of thioredoxins and glutaredoxins as electron donors to two distinct classes of Arabidopsis plastidial methionine sulfoxide reductases B

被引：86

作者：

Dos Santos, Christina Vieira ^{[1
]}

Laugier, Edith ^{[1
]}

Tarrago, Lionel ^{[1
]}

Massot, Vincent ^{[2
]}

Issakidis-Bourguet, Emmanuelle ^{[2
]}

Rouhier, Nicolas ^{[3
]}

Rey, Pascal ^{[1
]}

机构：

[1] CEA, DSV,IBEB, SBVME,UMR 6191, Lab Ecophysiol Mol Plant, F-13108 St Paul Les Durance, France

[2] Univ Paris 11, Ctr Natl Rech Sci, Inst Biotechnol Plant, Unit Mix Rech 8618, F-91405 Orsay, France

[3] Univ Nancy 1, INRA 1136, IFR,GEEF 110,Fac Sci, Unite Mixte Rech,Interact Arbres Microorganismes, F-54506 Vandoeuvre Les Nancy, France

来源：

FEBS LETTERS | 2007年 / 581卷 / 23期

关键词：

glutaredoxin; chloroplast; methionine; methionine sulfoxide reductase; plant; thioredoxin;

D O I：

10.1016/j.febslet.2007.07.081

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Methionine suffoxide reductases (MSRs) A and B reduce methionine sulfoxide (MetSO) S- and R-diastereomers, respectively, back to Met using electrons generally supplied by thioredoxin. The physiological reductants for MSRBs remain unknown in plants, which display a remarkable variety of thioredoxins (Trxs) and glutaredoxins (Grxs). Using recombinant proteins, we show that Arabidopsis plastidial MSRB1 and MSRB2, which differ regarding the number of presumed redox-active cysteines, possess specific reductants. Most simple-module Trxs, especially Trx m1 and Trx y2, are preferential and efficient electron donors towards MSRB2, while the doublemodule CDSP32 Trx and Grxs can reduce only MSRB1. This study identifies novel types of reductants, related to Grxs and peculiar Trxs, for MSRB proteins displaying only one redoxactive cysteine. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：4371 / 4376

页数：6

共 29 条

[1] The enzymology and biochemistry of methionine sulfoxide reductases [J].

Boschi-Muller, S ;

Olry, A ;

Antoine, M ;

Branlant, G .

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2005, 1703 (02) :231-238

[2] Potato plants lacking the CDSP32 plastidic thioredoxin exhibit overoxidation of the BAS1 2-cysteine peroxiredoxin and increased lipid peroxidation in thylakoids under photooxidative stress [J].

Broin, M ;

Rey, P .

PLANT PHYSIOLOGY, 2003, 132 (03) :1335-1343

[3] The plastidic 2-cysteine peroxiredoxin is a target for a thioredoxin involved in the protection of the photosynthetic apparatus against oxidative damage [J].

Broin, M ;

Cuiné, S ;

Eymery, F ;

Rey, P .

PLANT CELL, 2002, 14 (06) :1417-1432

[4] ENZYMATIC REDUCTION OF PROTEIN-BOUND METHIONINE SULFOXIDE [J].

BROT, N ;

WEISSBACH, L ;

WERTH, J ;

WEISSBACH, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (04) :2155-2158

[5] Characterization of plastidial thioredoxins from Arabidopsis belonging to the new y-type [J].

Collin, V ;

Lamkemeyer, P ;

Miginíac-Maslow, M ;

Hirasawa, M ;

Knaff, DB ;

Dietz, KJ ;

Issakidis-Bourguet, E .

PLANT PHYSIOLOGY, 2004, 136 (04) :4088-4095

[6] The Arabidopsis plastidial thioredoxins -: New functions and new insights into specificity [J].

Collin, V ;

Issakidis-Bourguet, E ;

Marchand, C ;

Hirasawa, M ;

Lancelin, JM ;

Knaff, DB ;

Miginiac-Maslow, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (26) :23747-23752

[7] The oxidative environment and protein damage [J].

Davies, MJ .

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2005, 1703 (02) :93-109

[8] Plant thioredoxins are key actors in the oxidative stress response [J].

Dos Santos, Christina Vieira ;

Rey, Pascal .

TRENDS IN PLANT SCIENCE, 2006, 11 (07) :329-334

[9] The Arabidopsis plastidic methionine sulfoxide reductase B proteins.: Sequence and activity characteristics, comparison of the expression with plastidic methionine sulfoxide reductase A, and induction by photooxidative stress [J].

Dos Santos, CV ;

Cuiné, S ;

Rouhier, N ;

Rey, P .

PLANT PHYSIOLOGY, 2005, 138 (02) :909-922

[10] Repair of oxidized proteins - Identification of a new methionine sulfoxide reductase [J].

Grimaud, R ;

Ezraty, B ;

Mitchell, JK ;

Lafitte, D ;

Briand, C ;

Derrick, PJ ;

Barras, F .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (52) :48915-48920

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