Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium

被引:122
作者
Stappenbeck, TS [1 ]
Wong, MH [1 ]
Saam, JR [1 ]
Mysorekar, IU [1 ]
Gordon, JI [1 ]
机构
[1] Washington Univ, Sch Med, Dept Mol Biol & Pharmacol, St Louis, MO 63110 USA
关键词
D O I
10.1016/S0955-0674(98)80110-5
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The mouse intestinal epithelium undergoes rapid renewal throughout life, thereby requiring continuous coordination of its cellular proliferation, differentiation, and death programs. Recent advances in our understanding of this process have highlighted some of the molecules that regulate renewal and their potential roles in gut neoplasia.
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收藏
页码:702 / 709
页数:8
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