Three new glycolipids from a Red Sea sponge of the genus Erylus

被引：18

作者：

Goobes, R

Rudi, A

Kashman, Y

Ilan, M

Loya, Y

机构：

[1] TEL AVIV UNIV,SCH CHEM,IL-69978 RAMAT AVIV,ISRAEL

[2] TEL AVIV UNIV,DEPT ZOOL,IL-69978 RAMAT AVIV,ISRAEL

来源：

TETRAHEDRON | 1996年 / 52卷 / 23期

关键词：

D O I：

10.1016/0040-4020(96)00363-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new cytotoxic glycolipids, erylusamine TA (8), erylusine (9) and erylusidine (10) have been isolated from a Red Sea sponge tentatively identified as Erylus cf. lendenfeldi. The structure of the three compounds was determined by interpretation of 2D NMR and FABMS data as trisaccharides of long-chain oxodihydroxyfatty acid amides formed with N,N-dimethyl-1,5-pentanediamine to yield 8 with omega-N,N-dimethylaminobutyl-N-methyl-1,3 -propanediamine to yield 9 and with 4-(aminobutyl) guanidine to yield 10 (R(3)=COCH2CH(CH3)(2)). Copyright (C) 1996 Elsevier Science Ltd

引用

收藏

页码：7921 / 7928

页数：8

相关论文

共 12 条

[1] CHARGE-REMOTE FRAGMENTATIONS - ANALYTICAL APPLICATIONS AND FUNDAMENTAL-STUDIES [J].

ADAMS, J .

MASS SPECTROMETRY REVIEWS, 1990, 9 (02) :141-186

[2] NMR-SPECTROSCOPY IN THE STRUCTURAL ELUCIDATION OF OLIGOSACCHARIDES AND GLYCOSIDES [J].

AGRAWAL, PK .

PHYTOCHEMISTRY, 1992, 31 (10) :3307-3330

[3] CORRELATION OF PROTON AND N-15 CHEMICAL-SHIFTS BY MULTIPLE QUANTUM NMR [J].

BAX, A ;

GRIFFEY, RH ;

HAWKINS, BL .

JOURNAL OF MAGNETIC RESONANCE, 1983, 55 (02) :301-315

[4] H-1 AND C-13 ASSIGNMENTS FROM SENSITIVITY-ENHANCED DETECTION OF HETERONUCLEAR MULTIPLE-BOND CONNECTIVITY BY 2D MULTIPLE QUANTUM NMR [J].

BAX, A ;

SUMMERS, MF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (08) :2093-2094

[5] PRACTICAL ASPECTS OF TWO-DIMENSIONAL TRANSVERSE NOE SPECTROSCOPY [J].

BAX, A ;

DAVIS, DG .

JOURNAL OF MAGNETIC RESONANCE, 1985, 63 (01) :207-213

[6] THE STRUCTURE OF ERYLOSIDE A, A NEW ANTITUMOR AND ANTIFUNGAL 4-METHYLATED STEROIDAL GLYCOSIDE FROM THE SPONGE ERYLUS-LENDENFELDI [J].

CARMELY, S ;

ROLL, M ;

LOYA, Y ;

KASHMAN, Y .

JOURNAL OF NATURAL PRODUCTS, 1989, 52 (01) :167-170

[7] STRUCTURE CHARACTERIZATION BY 2-DIMENSIONAL NMR-SPECTROSCOPY, OF 2 MARINE TRITERPENE OLIGOGLYCOSIDES FROM A PACIFIC SPONGE OF THE GENUS ERYLUS [J].

DAURIA, MV ;

PALOMA, LG ;

MINALE, L ;

RICCIO, R .

TETRAHEDRON, 1992, 48 (03) :491-498

[8] ERYLOSIDE-E FROM AN ATLANTIC SPONGE ERYLUS-GOFFRILLERI [J].

GULAVITA, NK ;

WRIGHT, AE ;

KELLYBORGES, M ;

LONGLEY, RE ;

YARWOOD, D ;

SILLS, MA .

TETRAHEDRON LETTERS, 1994, 35 (25) :4299-4302

[9] A TRITERPENE TETRASACCHARIDE, FORMOSIDE, FROM THE CARIBBEAN CHORISTIDA SPONGE ERYLUS-FORMOSUS [J].

JASPARS, M ;

CREWS, P .

TETRAHEDRON LETTERS, 1994, 35 (41) :7501-7504

[10]

MARTSON A, 1994, J CHROMATOGR A, V658, P315