Patterns of renal disease in South Africa

被引:9
作者
Naicker, S
机构
[1] Univ Natal, Sch Med, Dept Med, ZA-4001 Durban, South Africa
[2] Addington Hosp, Renal Unit, Durban, South Africa
关键词
glomerulonephritis; hypertension; renal disease; renal failure;
D O I
10.1111/j.1440-1797.1998.tb00466.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The prevalence and patterns of renal disease in the different racial groups in South Africa is reviewed. South Africa is populated by four groups: Blacks, Whites, Indians and 'Coloured' or Mixed race. In 1994, the South African Dialysis and Transplant Registry (SADTR) recorded 3399 patients (99 pmp) on treatment for end-stage renal failure (ESRF). Glomerulonephritis (GN) was recorded as the cause of ESRF in 1771 (52.1%) patients and hypertension (HPT) in 1549 (45.6%) patients. In a study of 394 patients with ESRF in our unit, HPT was the cause of ESRF in 32% of Blacks and 24% of Indians, GN in 25% of Blacks and Indians and 33% of 'Coloured' patients, while analgesic nephropathy caused ESRF in 33% of White patients. A study of 3632 patients with ESRF reported HPT as the aetiology in 4.3% of Whites, 13.8% of Indians and 34.6% of Blacks, with 57% of the latter having malignant hypertension. Of adult Black patients with primary GN, 36% had mesangiocapillary GN, while 21% had membranous GN and 10.7% minimal change disease. Black children have a low prevalence of minimal change disease: 13.5% compared with 75% in Indians. IgA nephropathy is rare in Blacks and has been reported in two patients in another study. Hepatitis B infection occurred in 73% of Black children with membranous GN. Prevalence data for hepatitis C-associated GN is lacking, but antibody-positive figures of 4.8-21% have been reported in South African dialysis and transplant patients. Prevalence figures for HIV-associated renal disease are not available. Public health measures are being actively implemented and should modify the prevalence and pattern of renal disease in South Africa.
引用
收藏
页码:S21 / S24
页数:4
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