Regioselective alkylation of 2-phenylpyridines with terminal alkenes via C-H bond activation by a rhodium catalyst

被引：67

作者：

Lim, YG

Kang, JB

Kim, YH

机构：

[1] KOREA ADV INST SCI & TECHNOL,DEPT CHEM,YUSONG GU,TAEJON 305701,SOUTH KOREA

[2] AGCY DEF DEV,DIV CHEM,TAEJON 305600,SOUTH KOREA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 17期

关键词：

D O I：

10.1039/p19960002201

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Phenylpyridine 1a reacts with various terminal alkenes in the presence of a rhodium(I) complex catalyst to give the corresponding mono ortho-alkylated products 2a-i and doubly alkylated products 3a-b (9:1), The same reaction using 3-methyl-2-phenylpyridine 1b gives the mono alkylated products 2j-n exclusively under the same reaction conditions due to steric hindrance between the methyl group of the pyridine and the alkyl group of 2j-n.

引用

页码：2201 / 2206

页数：6

共 48 条

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