Towards a European strategy for controlling antibiotic resistance - Nijmegen, Holland August 29-31, 1999

被引:13
作者
Gould, IM [1 ]
MacKenzie, EM
Struelens, MJ
van der Meer, JMW
机构
[1] Aberdeen Royal Infirm, Dept Med Microbiol, Aberdeen AB25 2ZN, Scotland
[2] Univ Brussels, Erasme Hosp, Dept Med Microbiol, Brussels, Belgium
[3] Dept Gen Internal Med, Nijmegen, Netherlands
关键词
D O I
10.1046/j.1469-0691.2000.00161.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A group of experts met under the auspices of the European Science Foundation, the European Medical Research Council and the European Society of Clinical Microbiology and Infectious Diseases to discuss formulation of a European strategy on the control of antibiotic resistance in Europe. This is a report of the meeting which was used as the basis for a European Commission grant application. The need for a common strategy to make best use of scarce resources was agreed and it was concluded that that first stage (discussed in this article) is to collate existing data on resistance rates, antibiotic consumption, antibiotic stewardship, infection control and molecular typing methods. Consensus reached from analysis of these data can direct us to the most appropriate controlled trials. While it is accepted that there is a widely held perception that the medical profession has been slow to react to the problem of antibiotic resistance, much more work still needs to be carried out before we can recommend, implement and trial definitive control measures. In the meantime, however, all reasonable efforts should be made to reduce antibiotic consumption without compromising patient care, establish cost-effective surveillance systems using existing laboratory generated data, improve hygiene in our hospitals and better define the molecular basis of antibiotic resistance.
引用
收藏
页码:670 / 674
页数:5
相关论文
共 24 条
[1]  
Arason VA, 1996, BMJ-BRIT MED J, V313, P387
[2]  
BAGER F, 1999, DANMAP 99 CONSUMPTIO
[3]   Comparison of glycopeptide-resistant Enterococcus faecium isolates and glycopeptide resistance genes of human and animal origins [J].
Descheemaeker, PRM ;
Chapelle, S ;
Devriese, LA ;
Butaye, P ;
Vandamme, P ;
Goossens, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (08) :2032-2037
[4]   Strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in hospitals - A challenge to hospital leadership [J].
Goldmann, DA ;
Weinstein, RA ;
Wenzel, RP ;
Tablan, OC ;
Duma, RJ ;
Gaynes, RP ;
Schlosser, J ;
Martone, WJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 275 (03) :234-240
[5]   Community acquired infections and bacterial resistance [J].
Goossens, H ;
Sprenger, MJW .
BRITISH MEDICAL JOURNAL, 1998, 317 (7159) :654-657
[6]  
Gould IM, 1996, J ANTIMICROB CHEMOTH, V38, P895
[7]   CONTROL OF ANTIBIOTIC USE IN THE UNITED-KINGDOM [J].
GOULD, IM .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1988, 22 (04) :395-397
[8]   Stewardship of antibiotic use and resistance surveillance: the international scene [J].
Gould, IM .
JOURNAL OF HOSPITAL INFECTION, 1999, 43 :S253-S260
[9]   An outbreak of multiply-resistant Klebsiella pneumoniae in the Grampian region of Scotland [J].
Hobson, RP ;
MacKenzie, FM ;
Gould, IM .
JOURNAL OF HOSPITAL INFECTION, 1996, 33 (04) :249-262
[10]   Antibiotic policies in Central/Eastern Europe (CEE) after 1990 [J].
Krcmery, V ;
Gould, IM .
JOURNAL OF HOSPITAL INFECTION, 1999, 43 :S269-S274