Androgen receptor outwits prostate cancer drugs

被引：128

作者：

Isaacs, JT ^{[1
]}

Isaacs, WB

机构：

[1] Johns Hopkins Univ, Sch Med, Sidney Kimmel Ctr Comprehens Canc, Baltimore, MD 21287 USA

[2] Johns Hopkins Univ, Sch Med, Dept Urol, Baltimore, MD 21287 USA

来源：

NATURE MEDICINE | 2004年 / 10卷 / 01期

关键词：

D O I：

10.1038/nm0104-26

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Almost all prostate cancer patients become resistant to therapy that blocks androgen-mediated cell proliferation. The key to this resistance may lie in expression of the androgen receptor itself (pages 33-39).

引用

页码：26 / 27

页数：3

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