Frontiers in glycomics: Bioinformatics and biomarkers in disease - An NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11-13,2006)

被引:115
作者
Packer, Nicolle H. [1 ]
von der Lieth, Claus-Wilhelm [2 ]
Aoki-Kinoshita, Kiyoko F. [3 ]
Lebrilla, Carlito B. [4 ]
Paulson, James C. [5 ]
Raman, Rahul [6 ]
Rudd, Pauline [7 ]
Sasisekharan, Ram [6 ]
Taniguchi, Naoyuki [8 ]
York, William S. [9 ]
机构
[1] Macquarie Univ, CORE Biomol Frontiers, Dept Chem & Biochem Sci, Sydney, NSW 2109, Australia
[2] German Canc Res Ctr, D-6900 Heidelberg, Germany
[3] Soka Univ, Tokyo, Japan
[4] Univ Calif Davis, Davis, CA 95616 USA
[5] Scripps Res Inst, La Jolla, CA USA
[6] MIT, Cambridge, MA 02139 USA
[7] Univ Coll Dublin, Dublin 2, Ireland
[8] Osaka Univ, Osaka, Japan
[9] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA
关键词
Bioinformatics; biomarkers; glycobiology; glycomics;
D O I
10.1002/pmic.200700917
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Key issues relating to glycomics research were discussed after the workshop entitled "Frontiers in Glycomics: Bioinformatics and Biomarkers in Disease" by two focus groups nominated by the organizers. The groups focused on two themes: (i) glycomics as the new frontier for the discovery of biomarkers of disease and (ii) requirements for the development of informatics for glycomics and glycobiology. The mandate of the focus groups was to build consensus on these issues and develop a summary of findings and recommendations for presentation to the NIH and the greater scientific community. A list of scientific priorities was developed, presented, and discussed at the workshops. Additional suggestions were solicited from workshop participants and collected using the workshop mailing list. The results are summarized in this 'White Paper, authored by the co-chairs of the focus groups.
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页码:8 / 20
页数:13
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