Expression of Vibrio vulnificus capsular polysaccharide inhibits biofilm formation

被引:106
作者
Joseph, LA [1 ]
Wright, AC [1 ]
机构
[1] Univ Florida, Dept Food Sci & Human Nutr, Aquat Food Prod Lab, Gainesville, FL 32611 USA
关键词
D O I
10.1128/JB.186.3.889-893.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Vibrio vulnificus is a human pathogen that produces lethal septicemia in susceptible persons, and the primary virulence factor for this organism is capsular polysaccharide (CPS). The role of the capsule in V. vulnificus biofilms was examined under a variety of conditions, by using either defined CPS mutants or spontaneous CPS expression phase variants derived from multiple strains. CPS expression was shown to inhibit attachment and biofilm formation, which contrasted with other studies describing polysaccharides as integral to biofilms in related species.
引用
收藏
页码:889 / 893
页数:5
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