Taking control of G-quadruplexes

被引:5
作者
Baumann, P
机构
[1] Stowers Inst Med Res, Kansas City, MO 64110 USA
[2] Univ Kansas, Med Ctr, Dept Biochem & Mol Biol, Kansas City, KS 66160 USA
关键词
D O I
10.1038/nsmb1005-832
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Telomeres are crucial for maintaining the integrity of the genome. Several alternative structures have been proposed for these caps, and understanding their biological significance is a matter of great interest. Probing of native telomeres now reveals that telomere end-binding proteins may control the formation of G-quadruplex DNA in vivo.
引用
收藏
页码:832 / 833
页数:2
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