Polar localization of a soluble methyl-accepting protein of Pseudomonas aeruginosa

被引:34
作者
Bardy, SL [1 ]
Maddock, JR [1 ]
机构
[1] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA
关键词
D O I
10.1128/JB.187.22.7840-7844.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A soluble methyl-accepting chemotaxis protein (MCP) of Pseudomonas aeruginosa, McpS, showed polar localization by immunofluorescence microscopy. Overexpression of McpS resulted in a dominant-negative effect on chemotaxis and caused a loss of polar clustering of the general MCP population. The polar localization of a soluble MCP defines a third, and unexpected, paradigm for cellular MCP localization.
引用
收藏
页码:7840 / 7844
页数:5
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