Metagenomics-based drug discovery and marine microbial diversity

被引:60
作者
Li, X
Qin, L
机构
[1] Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China
[2] CaTech Corp Ltd, Shatin, Hong Kong, Peoples R China
关键词
D O I
10.1016/j.tibtech.2005.08.006
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
As the global threat of drug-resistant pathogens continues to rise, new strategies and resources are required to accelerate and advance the drug discovery process. We believe that rapid progress in metagenomics has opened up a new era in the study of marine microbial diversity that enables direct access to the genomes of numerous uncultivable microorganisms. This review outlines recent developments and future trends in metagenomics-based drug discovery in marine microbial communities and their associated chemical prosperity.
引用
收藏
页码:539 / 543
页数:5
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