Successful treatment of aggressive post transplant lymphoproliferative disorder using Rituximab

被引：15

作者：

O'dwyer, ME ^{[1
]}

Launder, T ^{[1
]}

Rabkin, JM ^{[1
]}

Nichols, CR ^{[1
]}

机构：

[1] Oregon Hlth & Sci Univ, Div Hematol & Med Oncol, Div Transplant Surg, Portland, OR 97201 USA

来源：

LEUKEMIA & LYMPHOMA | 2000年 / 39卷 / 3-4期

关键词：

post transplant lymphoproliferative disorder; treatment; Rituximab; CD20; EBV; immunosuppression; organ;

D O I：

10.3109/10428190009065842

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 52 year-old female developed a histologically aggressive, Epstein-Barr virus positive. lymphoproliferative disorder involving the brain and liver 4 months following a combined kidney/pancreas transplant. Following a brief trial of reduced immunosuppression, she was treated with rituximab. Despite subsequent re-intensification of immunosuppression, the lesions showed continued regression with almost complete disappearance by 5 months. Rituximab appears to be a safe, effective treatment for post transplant lymphoproliferative disorder.

引用

页码：411 / 419

页数：9

共 14 条

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