Carbohydrate building blocks in heterocyclic chemistry. Synthetic studies directed towards the herbicidins

被引：9

作者：

Binch, HM

Griffin, AM

Gallagher, T

机构：

[1] School of Chemistry, University of Bristol

来源：

PURE AND APPLIED CHEMISTRY | 1996年 / 68卷 / 03期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1351/pac199668030589

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recent synthetic studies directed towards the herbicidin class of nucleosides are described Aldehyde 7, incorporating the requisite adenine unit, has been prepared but failed to undergo base-induced aldol reactions with ketone 3. This problem was overcome using the cerium enolate corresponding to 3, which is generated from alpha-bromoketone 9. Reaction of this species with aldehyde 7 leads to the enone 8.

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页码：589 / 592

页数：4

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