A combinatorial approach to surface-confined cation sensors in water

被引：44

作者：

Zimmerman, R ^{[1
]}

Basabe-Desmonts, L ^{[1
]}

van der Baan, F ^{[1
]}

Reinhoudt, DN ^{[1
]}

Crego-Calama, M ^{[1
]}

机构：

[1] Univ Twente, Dept Supramol Chem & Technol, MESA, Inst Nanotechnol, NL-7500 AE Enschede, Netherlands

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2005年 / 15卷 / 27-28期

关键词：

D O I：

10.1039/b502102b

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A novel material for sensing cations in water via fluorescence spectroscopy is presented. The material consists of a glass substrate functionalized with a series of fluorescent self-assembled monolayers. Parallel modification with pairs of fluorophore-binding molecules of monolayers formed on glass yield a library of sensitive glass substrates. Measurements of the changes in fluorescence intensity of the layers upon addition of aqueous solutions of Cu2+, Co2+, Ca2+ and Pb2+ confirmed the ability of the monolayer library to produce a "fingerprint" response for separate analytes with a high reproducibility. This new protocol for fabrication of sensitive probes in glass is suitable for array fabrication in small size substrates. Additionally, the covalent attachment of the fluorophore moieties to the monolayer allows monitoring of the integrity of the monolayer in time in contact with solutions. To the best of our knowledge this is the first example of sensing of cations in water by a self-assembled monolayer on glass.

引用

页码：2772 / 2777

页数：6

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