Nutritional control via Tor signaling in Saccharomyces cerevisiae

被引：94

作者：

Rohde, John R. ^{[1
]}

Bastidas, Robert ^{[2
]}

Puria, Rekha ^{[2
]}

Cardenas, Maria E. ^{[2
]}

机构：

[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada

[2] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2008年 / 11卷 / 02期

关键词：

D O I：

10.1016/j.mib.2008.02.013

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.

引用

页码：153 / 160

页数：8

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