Formation and reduction reactions of 3-indol-3-yl-isoxazolidines

被引：19

作者：

CoutouliArgyropoulou, E

MalamidouXenikaki, E

Stampelos, XN

Alexopoulou, IN

机构：

[1] Department of Chemistry, Aristotelian Univ. of Thessaloniki

来源：

TETRAHEDRON | 1997年 / 53卷 / 02期

关键词：

D O I：

10.1016/S0040-4020(96)01013-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3-Dipolar cycloaddition reactions of C-(1-methylindol-3-yl)-N-methylnitrone (1) with carbonyl substituted dipolarophiles lead to the formation of indolyl-isoxazolidines 3-6. Further reduction of the cycloadducts bearing a 5-methoxycarbonyl substituent give the pyrrolidinones 8,10. The stereoselectivity of the reactions and the structure elucidation of the products are discussed. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：707 / 718

页数：12

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