Transcriptional regulation by the phosphorylation-dependent factor CREB

被引：2083

作者：

Mayr, B ^{[1
]}

Montminy, M ^{[1
]}

机构：

[1] Salk Inst Biol Studies, La Jolla, CA 92037 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 08期

关键词：

D O I：

10.1038/35085068

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The transcription factor CREB - for 'cyclic AMP response element-binding protein' functions in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in learning and memory. CREB is phosphorylated in response to various signals, but how is specificity achieved in these signalling pathways?

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收藏

页码：599 / 609

页数：11

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