Integrin-collagen binding

被引：35

作者：

Tuckwell, D

Humphries, M

机构：

[1] Wellcome Trust Ctr. Cell-Matrix Res., School of Biological Sciences, University of Manchester, Manchester, M13 9PT, Oxford Road

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 1996年 / 7卷 / 05期

基金：

英国惠康基金;

关键词：

A-domain; collagen; integrin; von Willebrand factor;

D O I：

10.1006/scdb.1996.0079

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cell adhesion to collagens is mediated by the integrins alpha 1 beta 1 and alpha 2 beta 1, both of which bind a range of collagens including types I, TV and VT. In this article, we review studies that have attempted to define the molecular basis of integrin-collagen binding In particular, we focus On the active sites within both ligands and receptors that are responsible for binding. (C) 1996 Academic Press Ltd

引用

页码：649 / 657

页数：9

共 61 条

[1]

ANDRIEUX A, 1991, J BIOL CHEM, V266, P14201

[2] ATTACHMENT OF CELLS TO BASEMENT-MEMBRANE COLLAGEN TYPE-IV [J].

AUMAILLEY, M ;

TIMPL, R .

JOURNAL OF CELL BIOLOGY, 1986, 103 (04) :1569-1575

[3] CELL ATTACHMENT PROPERTIES OF COLLAGEN TYPE-VI AND ARG-GLY-ASP DEPENDENT BINDING TO ITS ALPHA-2(VI) AND ALPHA-3(VI) CHAINS [J].

AUMAILLEY, M ;

MANN, K ;

VONDERMARK, H ;

TIMPL, R .

EXPERIMENTAL CELL RESEARCH, 1989, 181 (02) :463-474

[4]

BAJT ML, 1992, J BIOL CHEM, V267, P3789

[5]

BAJT ML, 1994, J BIOL CHEM, V269, P20913

[6] Specificity of integrin I-domain-ligand binding [J].

Calderwood, DA ;

Tuckwell, DS ;

Humphries, MJ .

BIOCHEMICAL SOCIETY TRANSACTIONS, 1995, 23 (04) :S504-S504

[7]

CARDARELLI PM, 1992, J BIOL CHEM, V267, P23159

[8] MONOCLONAL-ANTIBODIES THAT BLOCK THE ACTIVITY OF LEUKOCYTE FUNCTION-ASSOCIATED ANTIGEN-1 RECOGNIZE 3 DISCRETE EPITOPES IN THE INSERTED DOMAIN OF CD11A [J].

CHAMPE, M ;

MCINTYRE, BW ;

BERMAN, PW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (03) :1388-1394

[9] MULTIPLE FUNCTIONAL FORMS OF THE INTEGRIN VLA-2 CAN BE DERIVED FROM A SINGLE ALPHA(2) CDNA CLONE - INTERCONVERSION OF FORMS INDUCED BY AN ANTI-BETA(1) ANTIBODY [J].

CHAN, BMC ;

HEMLER, ME .

JOURNAL OF CELL BIOLOGY, 1993, 120 (02) :537-543

[10]

COLLER BS, 1989, BLOOD, V74, P182

← 1 2 3 4 5 6 7 →