Novel delivery methods to achieve immunomodulation

被引：12

作者：

Gould, David J.

Chernajovsky, Yuti ^{[1
]}

机构：

[1] Willam Harvey Res Inst, Bone & Joint Res Unit, London EC1M 6BQ, England

[2] Univ London, Queen Marys Sch Med & Dent, London EC1M 6BQ, England

来源：

CURRENT OPINION IN PHARMACOLOGY | 2007年 / 7卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/j.coph.2007.05.002

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

Immunomodulation in infectious diseases, cancer, cardiovascular disease and autoimmunity can now be targeted by sophisticated protein design, altering cellular responses by increasing therapeutic cell numbers ex vivo and then reimplanting, or altering cell function by gene transfer of cells ex vivo. In the last year, vaccination has been applied to modulate responses to autoantigens, allergens, viral or cancer antigens. The application of these technologies has entered the clinical arena and is having a positive impact on the treatment and prevention of human diseases.

引用

收藏

页码：445 / 450

页数：6

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