Parkinson's disease: in vivo assessment of disease progression using positron emission tomography

被引：33

作者：

Au, WL ^{[1
]}

Adams, JR ^{[1
]}

Troiano, AR ^{[1
]}

Stoessl, AJ ^{[1
]}

机构：

[1] Univ British Columbia, Vancouver Hosp & Hlth Sci Ctr, Pacific Parkinsons Res Ctr, Vancouver, BC V6T 2B5, Canada

来源：

MOLECULAR BRAIN RESEARCH | 2005年 / 134卷 / 01期

关键词：

Parkinson's disease; progression; positron emission tomography;

D O I：

10.1016/j.molbrainres.2004.09.028

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Over the past two decades, positron emission tomography (PET) has provided valuable insights into the mechanisms of nigrostriatal degeneration in Parkinson's disease (PD). Furthermore, it allows the in vivo assessment of disease progression and the evaluation of treatment interventions. In this review, we shall discuss some of the issues and concerns that arise with the use of PET as a surrogate marker of disease progression in Parkinson's disease. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：24 / 33

页数：10

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