A novel hindered macrocyclic tetramine containing two bispidine units. A new type of proton sponge

被引：34

作者：

Miyahara, Y ^{[1
]}

Goto, K ^{[1
]}

Inazu, T ^{[1
]}

机构：

[1] Kyushu Univ, Fac Sci, Dept Chem, Higashi Ku, Fukuoka 8128581, Japan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(01)00341-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel cyclam-like macrocyclic tetramine la was synthesized via coupling of bispidine and its bis(alpha -chloroacetamide) followed by reduction. Strongly basic but encrypted nitrogens of la were found to abstract a proton from chloroform to form dichlorocarbene. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：3097 / 3099

页数：3

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