Photoprotective activity of Buddleja scordioides

被引：47

作者：

Acevedo, JGA ^{[1
]}

Castañeda, CMC

Benitez, FJC

Durán, DA

Barroso, VR

Martínez, CG

Muñoz, LJL

Martínez, CA

de Vivar, AR

机构：

[1] Univ Nacl Autonoma Mexico, Lab Fitoquim, Unidad Biol Tecnol & Prototipos, FES Iztacala, Tlalnepantla 54090, Mexico

[2] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

来源：

FITOTERAPIA | 2005年 / 76卷 / 3-4期

关键词：

Buddleja scordioides; linarin; verbascoside; photoprotective activity; sun protection factor;

D O I：

10.1016/j.fitote.2005.03.009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular death was evaluated by challenge experiments using Escherichia coli. Verbascoside and linarin acetate showed the highest protection. The sun protection factor (SPF) of the methanolic extract, linarin, linarin acetate, and verbascoside was evaluated by guinea pig bioassays. Verbascoside showed the largest SPF measurement. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：301 / 309

页数：9

共 18 条

[1]

[Anonymous], PLANTAS MED HERBARIO

[2] THE STRUCTURES OF BUDDLEOFLAVONOLOSIDE (LINARIN) AND OF BUDDLEOFLAVONOL (ACACETIN) [J].

BAKER, W ;

HEMMING, R ;

OLLIS, WD .

JOURNAL OF THE CHEMICAL SOCIETY, 1951, (MAR) :691-695

[3] TIME-DEPENDENT DECREASE IN SUNSCREEN PROTECTION AGAINST CHRONIC PHOTODAMAGE IN UVB-IRRADIATED HAIRLESS MOUSE SKIN [J].

BISSETT, DL ;

MCBRIDE, JF ;

HANNON, DP ;

PATRICK, LF .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1991, 9 (3-4) :323-334

[4] Flavonoids as potential protective agents against photo-oxidative skin damage [J].

Bonina, F ;

Lanza, M ;

Montenegro, L ;

Puglisi, C ;

Tomaino, A ;

Trombetta, D ;

Castelli, F ;

Saija, A .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1996, 145 (1-2) :87-94

[5] A ROLE FOR SUNLIGHT IN SKIN-CANCER - UV-INDUCED P53 MUTATIONS IN SQUAMOUS-CELL CARCINOMA [J].

BRASH, DE ;

RUDOLPH, JA ;

SIMON, JA ;

LIN, A ;

MCKENNA, GJ ;

BADEN, HP ;

HALPERIN, AJ ;

PONTEN, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (22) :10124-10128

[6]

Eisenstadt Eric, 1994, P297

[7] Sunscreens and photocarcinogenesis: An objective assessment [J].

Elmets, CA ;

Anderson, CY .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1996, 63 (04) :435-440

[8]

GEISMAN TA, 1962, CHEM FLAVONOID COMPU

[9] The effects of two UVB radiation-absorbing sunscreens on UV radiation-induced carcinogenesis, suppression of the contact hypersensitivity response and histological changes in the hairless mouse [J].

Kerr, C .

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 1998, 422 (01) :161-164

[10]

Liu MC, 1996, J FOOD DRUG ANAL, V4, P343

← 1 2 →