Lung Krupple-like factor: a quintessential player in T cell quiescence

被引:17
作者
Di Santo, JP [1 ]
机构
[1] Inst Pasteur, Unite Cytokines & Dev Lymphoide, F-75724 Paris 15, France
关键词
D O I
10.1038/90598
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The molecular events behind T cell quiescence are poorly understood. Evidence is now emerging that the transcription factor LKLF can potentially programme cells to a resting state in a c-Myc-dependent manner.
引用
收藏
页码:667 / 668
页数:2
相关论文
共 14 条
  • [1] Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway
    Buckley, AF
    Kuo, CT
    Leiden, JM
    [J]. NATURE IMMUNOLOGY, 2001, 2 (08) : 698 - 704
  • [2] CHAN X, 2000, J BIOL CHEM, V275, P18391
  • [3] CHEN X, 2001, IN PRESS J BIOL CHEM, V276
  • [4] Erythroid Kruppel-like factor (EKLF) coordinates erythroid cell proliferation and hemoglobinization in cell lines derived from EKLF null mice
    Coghill, E
    Eccleston, S
    Fox, V
    Cerruti, L
    Brown, C
    Cunningham, J
    Jane, S
    Perkins, A
    [J]. BLOOD, 2001, 97 (06) : 1861 - 1868
  • [5] POPULATION BIOLOGY OF LYMPHOCYTES: The flight for survival
    Freitas, AA
    Rocha, B
    [J]. ANNUAL REVIEW OF IMMUNOLOGY, 2000, 18 : 83 - 111
  • [6] Gene expression in antigen-specific CD8+ T cells during viral infection
    Grayson, JM
    Murali-Krishna, K
    Altman, JD
    Ahmed, R
    [J]. JOURNAL OF IMMUNOLOGY, 2001, 166 (02) : 795 - 799
  • [7] LKLF: A transcriptional regulator of single-positive T cell quiescence and survival
    Kuo, CT
    Veselits, ML
    Leiden, JM
    [J]. SCIENCE, 1997, 277 (5334) : 1986 - 1990
  • [8] γ chain required for naive CD4+ T cell survival but not for antigen proliferation
    Lantz, O
    Grandjean, I
    Matzinger, P
    Di Santo, JP
    [J]. NATURE IMMUNOLOGY, 2000, 1 (01) : 54 - 58
  • [9] Mateyak MK, 1999, MOL CELL BIOL, V19, P4672
  • [10] Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    Schluns, KS
    Kieper, WC
    Jameson, SC
    Lefrançois, L
    [J]. NATURE IMMUNOLOGY, 2000, 1 (05) : 426 - 432