Hydroxyapatite-coated orthopaedic screws as infection resistant materials: in vitro study

被引：57

作者：

Arciola, CR

Montanaro, L

Moroni, A

Giordano, M

Pizzoferrato, A

Donati, ME

机构：

[1] Inst Ortoped Rizzoli, Lab Biocompatibil Res Implant Mat, I-40136 Bologna, Italy

[2] Inst Ortoped Rizzoli, Orthopaed Div 9, I-40136 Bologna, Italy

[3] Univ Bologna, Dept Expt Pathol, I-40126 Bologna, Italy

来源：

BIOMATERIALS | 1999年 / 20卷 / 04期

关键词：

hydroxyapatite; stainless steel; orthopaedic screws; bacterial adherence; infection resistant material;

D O I：

10.1016/S0142-9612(98)00168-9

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The authors evaluated in vitro the adherence of a Staphylococcus epidermidis strain to hydroxyapatite-coated stainless-steel screws-used in orthopaedic surgery for external fracture fixation-in comparison with the adherence to uncoated screws. Evaluations were also performed on analogous groups of screws immersed for 72 and 168 h in a solution at 37 degrees C, in order to simulate the interstitial fluid in a simplified way. Adherence values on coated prostheses resulted significantly lower compared with those observed on metal prostheses, both in basal conditions and after immersion in saline solution. Moreover, both on coated and on uncoated screws a significant reduction in bacterial adherence was noted related to the duration of the prosthesis permanence in saline solution. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：323 / 327

页数：5

共 21 条

[1] 7 SURGICAL SILICONES RETAIN STAPHYLOCOCCUS-AUREUS DIFFERENTLY IN-VITRO [J].