Acupuncture and regulation of gastrointestinal function

被引:204
作者
Li, Hui [1 ,2 ]
He, Tian [1 ]
Xu, Qian [1 ]
Li, Zhe [1 ]
Liu, Yan [2 ]
Li, Fang [2 ]
Yang, Bo-Feng [2 ]
Liu, Cun-Zhi [1 ]
机构
[1] Capital Med Univ, Beijing Hosp Tradit Chinese Med, Acupuncture & Moxibust Dept, Beijing 100010, Peoples R China
[2] Tianjin Univ Tradit Chinese Med, Tianjin 300193, Peoples R China
基金
中国国家自然科学基金; 北京市自然科学基金;
关键词
Acupuncture; Gastrointestinal motility; Gastrointestinal barrier; Visceral sensitivity; Brain-gut axis; IRRITABLE-BOWEL-SYNDROME; CHRONIC VISCERAL HYPERSENSITIVITY; GUT BARRIER DYSFUNCTION; GASTRIC-MUCOSAL INJURY; NITRIC-OXIDE SYNTHASE; RECTAL DISTENSION; MANUAL ACUPUNCTURE; INTERSTITIAL-CELLS; DYSPEPSIA PATIENTS; RESTRAINT STRESS;
D O I
10.3748/wjg.v21.i27.8304
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
In China, acupuncture has been considered an effective method for treating gastrointestinal (GI) dysfunction diseases for thousands of years. In fact, acupuncture has gained progressive acceptance from both practitioners and patients worldwide. However, the therapeutic effects and underlying mechanisms in treating GI dysfunction have not yet been established due to a lack of systematic and comprehensive review articles. Therefore, the aim of this review is to discuss the efficacy of acupuncture as a treatment for GI dysfunction and the associated underlying mechanisms. A search of PubMed was conducted for articles that were published over the past 10 years using the terms "acupuncture", "gastrointestine", and other relevant keywords. In the following review, we describe the effect and underlying mechanisms of acupuncture on GI function from the perspectives of GI motility, visceral sensitivity, the GI barrier, and the brain-gut axis. The dual regulatory effects of acupuncture may manifest by promoting gastric peristalsis in subjects with low initial gastric motility, and suppressing peristalsis in subjects with active initial motility. In addition, the regulation of acupuncture on gastric motility may be intensity-dependent. Our findings suggest that further studies are needed to investigate the effects and more systematic mechanisms in treating GI dysfunction, and to promote the application of acupuncture for the treatment of GI diseases.
引用
收藏
页码:8304 / 8313
页数:10
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