Safety evaluation of fucoxanthin purified from Undaria pinnatifida

被引：38

作者：

Kadekaru, Takashi ^{[1
]}

Toyama, Hiroshi ^{[1
]}

Yasumoto, Takeshi ^{[1
]}

机构：

[1] JST, Okinawa Prefecture Collaborat Reg Ent Advancemene, Okinawa 9042234, Japan

来源：

JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI | 2008年 / 55卷 / 06期

关键词：

fucoxanthin; Undaria pinnatifida; safety evaluation;

D O I：

10.3136/nskkk.55.304

中图分类号：

TS2 [食品工业];

学科分类号：

0832 [食品科学与工程];

摘要：

A toxicity study was conducted on fucoxanthin (FX) purified from Undaria pinnatifida. Evaluation was made following the repeated oral dosing of purified FX (>= 95% purity) to rats for 28 days. In the 28-day, repeated oral dose test, purified FX did not show obvious toxicity. However, significant increases in total cholesterol and high-density lipoprotein cholesterol (HDL-C) levels were observed in the blood when the dose of FX was 10 mg/kg/day or higher.

引用

页码：304 / 308

页数：5