The gas-phase chemistry of cyclodextrin inclusion complexes

被引：129

作者：

Lebrilla, CB ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2001年 / 34卷 / 08期

关键词：

D O I：

10.1021/ar980125x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Complexes of cyclodextrins with amino acid analytes are produced in the gas phase and are ideal for the study of molecular recognition. In this Account, we discuss the evidence for the presence of gas-phase inclusion complexes and the nature of the interaction. The use of cyclodextrins as chiral selectors in gas-phase guest-exchange reactions is illustrated, and the nature of the enantioselectivity is discussed. The development of the enantioselective reaction into an analytical method for determining enantiomeric excess is also described.

引用

页码：653 / 661

页数：9

共 30 条

[1]

AHN S, 2000, IN PRESS J AM SOC MA

[2] ACTIVATION-ENERGIES FOR GAS-PHASE DISSOCIATIONS OF MULTIPLY CHARGED IONS FROM ELECTROSPRAY IONIZATION MASS-SPECTROMETRY [J].