First report of methicillin-resistant Staphylococcus aureus Cordobes/Chilean clone involved in nosocomial infections in Brazil

被引：20

作者：

Becker, A. P. ^{[1
,2
]}

Santos, O. ^{[1
]}

Castrucci, F. M. ^{[3
]}

Dias, C. ^{[1
,2
]}

Alves D'Azevedo, P. ^{[1
]}

机构：

[1] Univ Fed Ciencias Saude Porto Alegre, Porto Alegre, RS, Brazil

[2] Hosp Mae Deus, Porto Alegre, RS, Brazil

[3] Univ Fed Sao Paulo, Lab Especial Microbiol Clin, Sao Paulo, Brazil

来源：

EPIDEMIOLOGY AND INFECTION | 2012年 / 140卷 / 08期

关键词：

Cordobes/Chilean clone; methicillin resistant; MRSA; Staphylococcus aureus; EPIDEMIC CLONE; IDENTIFICATION; EVOLUTION; MRSA; SURVEILLANCE; BACTEREMIA; CORDOBA; SPREAD;

D O I：

10.1017/S095026881100210X

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

100235 [预防医学];

摘要：

Methicillin-resistant Staphylococcus aureus (MRSA) commonly causes infection in hospitalized patients. Resistance is due to the acquisition of mecA gene located on the chromosomal element SCCmec and to date 12 types have been identified. Specific epidemic clones of MRSA have emerged with enhanced ability to spread within and among hospitals and to cross national boundaries. We studied 30 isolates from patients with MRSA infections at two hospitals in Porto Alegre city from April to December, 2008 and determined their SCCmec type by PCR. Representative strains were typed by PFGE. Eighteen (60%) isolates carried SCCmec type III and had PFGE profiles clonally related to the previously characterized Brazilian epidemic clone, and 11 (36.7%) isolates with pulsotypes closely related to the Cordobes/Chilean clone harboured SCCmec type I. To the best of our knowledge, this is the first report of the appearance of Cordobes/Chilean clone involved in nosocomial infection in Brazil.

引用

页码：1372 / 1375

页数：4

共 21 条

[1]

Clinical and Laboratory Standards Institute (CLSI), 2010, M100S17 CLSI NCCLS

[2]

Spread of the Brazilian epidemic clone of a multiresistant MRSA in two cities in Argentina [J].

Coimbra, MVD ;

Teixeira, LA ;

Ramos, RLB ;

Predar, SC ;

Castello, L ;

Famiglietti, A ;

Vay, C ;

Klan, L ;

Figueiredo, AMS .

JOURNAL OF MEDICAL MICROBIOLOGY, 2000, 49 (02) :187-192

[3]

Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia:: A meta-analysis [J].

Cosgrove, SE ;

Sakoulas, G ;

Perencevich, EN ;

Schwaber, MJ ;

Karchmer, AW ;

Carmeli, Y .

CLINICAL INFECTIOUS DISEASES, 2003, 36 (01) :53-59

[4]

Two international methicillin-resistant Staphylococcus aureus clones endemic in a University Hospital in Patras, Greece [J].

de Sousa, MA ;

Bartzavali, C ;

Spiliopoulou, I ;

Sanches, IS ;

Crisóstomo, MI ;

de Lencastre, H .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (05) :2027-2032

[5]

Genotyping of methicillin-resistant Staphylococcus aureus isolates obtained in the Northeast region of Brazil [J].

de Sousa-Junior, F. C. ;

Silva-Carvalho, M. C. ;

Fernandes, M. J. B. C. ;

Vieira, M. F. P. ;

Pellegrino, F. L. P. C. ;

Figueiredo, A. M. S. ;

de Melo, M. C. N. ;

Milan, E. P. .

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2009, 42 (10) :877-881

[6]

The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA) [J].

Enright, MC ;

Robinson, DA ;

Randle, G ;

Feil, EJ ;

Grundmann, H ;

Spratt, BG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (11) :7687-7692

[7]

Dominance of EMRSA-15 and-16 among MRSA causing nosocomial bacteraemia in the UK:: analysis of isolates from the European Antimicrobial Resistance Surveillance System (EARSS) -: J Antimicrob Chemother 2001;: 48:143-144 [J].

Johnson, AP ;

Aucken, HM ;

Cavendish, S ;

Ganner, M ;

Wale, MCJ ;

Warner, M ;

Livermore, DM ;

Cookson, BD .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 48 (01) :143-144

[8]

Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States:: Establishing a national database [J].

McDougal, LK ;

Steward, CD ;

Killgore, GE ;

Chaitram, JM ;

McAllister, SK ;

Tenover, FC .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (11) :5113-5120

[9]

Update on the major clonal types of methicillin-resistant Staphylococcus aureus in the Czech Republic [J].

Melter, O ;

de Sousa, MA ;

Urbásková, P ;

Jakubu, V ;

Zemlicková, H ;

de Lencastre, H .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (11) :4998-5005

[10]

Secrets of success of a human pathogen:: molecular evolution of pandemic clones of meticillin-resistant Staphylocloccus aureus [J].

Oliveira, DC ;

Tomasz, A ;

de Lencastre, H .

LANCET INFECTIOUS DISEASES, 2002, 2 (03) :180-189

← 1 2 3 →