Nonspecific Interstitial Pneumonia: Prognostic Significance of High-Resolution Computed Tomography in 59 Patients

被引：9

作者：

Hozumi, Hironao ^{[1
]}

Nakamura, Yutaro ^{[1
]}

Johkoh, Takeshi ^{[2
]}

Sumikawa, Hiromitsu ^{[3
]}

Colby, Thomas V. ^{[4
]}

Karayama, Masato ^{[1
]}

Hayakawa, Hiroshi ^{[1
]}

Yokomura, Koushi ^{[1
]}

Imokawa, Shiro ^{[1
]}

Yasuda, Kazumasa ^{[1
]}

Toyoshima, Mikio ^{[1
]}

Suganuma, Hideki ^{[1
]}

Shirai, Toshihiro ^{[1
]}

Inui, Naoki ^{[1
]}

Suda, Takafumi ^{[1
]}

Nakamura, Hirotoshi ^{[1
]}

Chida, Kingo ^{[1
]}

机构：

[1] Hamamatsu Univ Sch Med, Div 2, Dept Internal Med, Higashi Ku, Hamamatsu, Shizuoka 4313192, Japan

[2] Kinki Cent Hosp, Mutual Aid Assoc Publ Sch Teachers, Dept Radiol, Itami, Hyogo, Japan

[3] Osaka Univ, Grad Sch Med, Dept Radiol, Osaka, Japan

[4] Mayo Clin Arizona, Dept Pathol, Scottsdale, AZ USA

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 2011年 / 35卷 / 05期

关键词：

nonspecific interstitial pneumonia; interstitial pneumonia; high resolution computed tomography; prognosis; IDIOPATHIC PULMONARY-FIBROSIS; THIN-SECTION CT; REVISED CRITERIA; DISEASE; CLASSIFICATION; SURVIVAL; PATTERN; FEATURES; SOCIETY;

D O I：

10.1097/RCT.0b013e31822a5883

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

100231 [临床病理学]; 100902 [航空航天医学];

摘要：

Objective: To retrospectively analyze the prognostic implications of high-resolution computed tomography (HRCT) findings for patients with biopsy-proven nonspecific interstitial pneumonia (NSIP). Methods: Fifty-nine patients with NSIP (25 idiopathic NSIP, 34 collagen-vascular disease-associated NSIP) were included. Two chest radiologists independently evaluated the extent, presence, and distribution of various HRCT findings. Cox hazards analysis was used to evaluate the relationship between HRCT findings and prognosis. Results: The 5-year survival rate was 83% and the 10-year survival rate was 66%. Univariate analysis revealed that the extent of areas with ground-glass attenuation without traction bronchi-bronchiolectasis and that of airs-pace consolidation were associated with favorable outcome, whereas that of intralobular reticular opacities was associated with worse prognosis. Multivariate analysis showed that the extent of air-space consolidation was an independent factor of favorable outcome. Conclusion: In NSIP, the extent of areas with ground-glass attenuation without traction bronchi-bronchiolectasis, air-space consolidation, and intralobular reticular opacities correlate with survival.

引用

页码：583 / 589

页数：7

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