Probiotics in the treatment of human inflammatory bowel diseases - Update 2008

被引：27

作者：

Fedorak, Richard Neil ^{[1
]}

Dieleman, Levinus Albert ^{[1
]}

机构：

[1] Univ Alberta, Zeidler Ledcor Ctr, Div Gastroenterol, Edmonton, AB T6G, Canada

来源：

JOURNAL OF CLINICAL GASTROENTEROLOGY | 2008年 / 42卷 / 06期

关键词：

Crohn's disease; inflammatory bowel diseases; pouchitis; probiotics; ulcerative colitis; Lactobacillus; Bifidobacterium; VSL#3; E. coli Nissle;

D O I：

10.1097/MCG.0b013e3181618ac7

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Probiotic research and clinical trials have been forging ahead over the last decade. Although much has been learnt in relation to probiotic intestinal epithelial-mucosal immune interactions, the evidence for substantial clinical efficacy of probiotics continues to progress much slower. This review outlines the probiotic clinical studies before 2005 that formed the foundation of probiotic clinical trials in inflammatory bowel disease and then examines indepth those inflammatory bowel disease probiotic clinical trials published after 2005 that are leading to new understanding of the role of probiotics in the induction and remission of inflammatory bowel disease in humans.

引用

页码：S97 / S103

页数：7

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