Model of transient oscillatory synchronization in the locust antennal lobe

被引：169

作者：

Bazhenov, M ^{[1
]}

Stopfer, M

Rabinovich, M

Huerta, R

Abarbanel, HDI

Sejnowski, TJ

Laurent, G

机构：

[1] Salk Inst Biol Studies, Howard Hughes Med Inst, Computat Neurobiol Lab, La Jolla, CA 92037 USA

[2] CALTECH, Div Biol, Pasadena, CA 91125 USA

[3] Univ Calif San Diego, Inst Nonlinear Sci, La Jolla, CA 92093 USA

[4] Univ Calif San Diego, Scripps Inst Oceanog, Dept Phys, La Jolla, CA 92093 USA

[5] Univ Calif San Diego, Scripps Inst Oceanog, Marine Phys Lab, La Jolla, CA 92093 USA

[6] Univ Calif San Diego, Dept Biol, La Jolla, CA 92093 USA

来源：

NEURON | 2001年 / 30卷 / 02期

关键词：

D O I：

10.1016/S0896-6273(01)00284-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Transient pairwise synchronization of locust antennal lobe (AL) projection neurons (PNs) occurs during odor responses. In a Hodgkin-Huxley-type model of the AL, interactions between excitatory PNs and inhibitory local neurons (LNs) created coherent network oscillations during odor stimulation. GABAergic interconnections between LNs led to competition among them such that different groups of LNs oscillated with periodic Ca2+ spikes during different 50-250 ms temporal epochs, similar to those recorded in vivo. During these epochs, LN-evoked IPSPs caused phase-locked, population oscillations in sets of postsynaptic PNs. The model shows how alternations of the inhibitory drive can temporally encode sensory information in networks of neurons without precisely tuned intrinsic oscillatory properties.

引用

页码：553 / 567

页数：15

共 47 条

[11] Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices [J].

Destexhe, A ;

Bal, T ;

McCormick, DA ;

Sejnowski, TJ .

JOURNAL OF NEUROPHYSIOLOGY, 1996, 76 (03) :2049-2070

[12]

Enright W. H., 1995, A survey of the explicit Runge-Kutta method

[13] Minimal model of oscillations and waves in the Limax olfactory lobe with tests of the model's predictive power [J].

Ermentrout, B ;

Flores, J ;

Gelperin, A .

JOURNAL OF NEUROPHYSIOLOGY, 1998, 79 (05) :2677-2689

[14] EEG ANALYSIS GIVES MODEL OF NEURONAL TEMPLATE-MATCHING MECHANISM FOR SENSORY SEARCH WITH OLFACTORY-BULB [J].

FREEMAN, WJ .

BIOLOGICAL CYBERNETICS, 1979, 35 (04) :221-234

[15] Dynamic optimization of odor representations by slow temporal patterning of mitral cell activity [J].

Friedrich, RW ;

Laurent, G .

SCIENCE, 2001, 291 (5505) :889-894

[16]

Gauck V, 2000, J NEUROSCI, V20, P3006

[17] ODOR-MODULATED COLLECTIVE NETWORK OSCILLATIONS OF OLFACTORY INTERNEURONS IN A TERRESTRIAL MOLLUSK [J].

GELPERIN, A ;

TANK, DW .

NATURE, 1990, 345 (6274) :437-440

[18] The number of synaptic inputs and the synchrony of large, sparse neuronal networks [J].

Golomb, D ;

Hansel, D .

NEURAL COMPUTATION, 2000, 12 (05) :1095-1139

[19] SYNCHRONIZATION PROPERTIES OF SPINDLE OSCILLATIONS IN A THALAMIC RETICULAR NUCLEUS MODEL [J].

GOLOMB, D ;

WANG, XJ ;

RINZEL, J .

JOURNAL OF NEUROPHYSIOLOGY, 1994, 72 (03) :1109-1126

[20] STIMULUS-SPECIFIC NEURONAL OSCILLATIONS IN ORIENTATION COLUMNS OF CAT VISUAL-CORTEX [J].

GRAY, CM ;

SINGER, W .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (05) :1698-1702

← 1 2 3 4 5 →