Continuous cell separation using novel magnetic quadrupole flow sorter

被引：180

作者：

Zborowski, M

Sun, LP

Moore, LR

Williams, PS

Chalmers, JJ

机构：

[1] Cleveland Clin Fdn, Dept Biomed Engn, Cleveland, OH 44195 USA

[2] Ohio State Univ, Dept Chem Engn, Columbus, OH 43210 USA

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 1999年 / 194卷 / 1-3期

基金：

美国国家卫生研究院;

关键词：

quadrupole field; magnetic colloid; immunomagnetic separation; cell separation; human lymphocytes;

D O I：

10.1016/S0304-8853(98)00581-2

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A laboratory prototype of a flow cell sorter based on magnetic quadrupole field was built and evaluated. The magnetic force acting on magnetically labeled cells in such a field has a 'centrifugal' character which provides a basis for the design of a continuous separation process. The sorter was tested on a model cell system of human peripheral lymphocytes labeled with magnetic colloid. (C) 1999 Published by Elsevier Science B.V. All rights reserved.

引用

页码：224 / 230

页数：7

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