Racial differences in the response to drugs - Pointers to genetic differences.

被引:130
作者
Wood, AJJ [1 ]
机构
[1] Vanderbilt Univ, Sch Med, Nashville, TN 37232 USA
关键词
D O I
10.1056/NEJM200105033441811
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1393 / 1396
页数:5
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共 15 条
[1]   Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications [J].
Aithal, GP ;
Day, CP ;
Kesteven, PJL ;
Daly, AK .
LANCET, 1999, 353 (9154) :717-719
[2]   Angiotensin-II type 1 receptor gene polymorphism and long-term survival in patients with idiopathic congestive heart failure [J].
Andersson, B ;
Blange, I ;
Sylvén, C .
EUROPEAN JOURNAL OF HEART FAILURE, 1999, 1 (04) :363-369
[3]   GEOGRAPHICAL INTERRACIAL DIFFERENCES IN POLYMORPHIC DRUG OXIDATION - CURRENT STATE OF KNOWLEDGE OF CYTOCHROMES P450 (CYP) 2D6 AND 2C19 [J].
BERTILSSON, L .
CLINICAL PHARMACOKINETICS, 1995, 29 (03) :192-209
[4]   Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction. [J].
Exner, DV ;
Dries, DL ;
Domanski, MJ ;
Cohn, JN .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (18) :1351-1357
[5]   Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer [J].
Furuta, T ;
Ohashi, K ;
Kamata, T ;
Takashima, M ;
Kosuge, K ;
Kawasaki, T ;
Hanai, H ;
Kubota, T ;
Ishizaki, T ;
Kaneko, E .
ANNALS OF INTERNAL MEDICINE, 1998, 129 (12) :1027-1030
[6]   ATTENUATION OF ISOPROTERENOL-MEDIATED VASODILATATION IN BLACKS [J].
LANG, CC ;
STEIN, CM ;
BROWN, RM ;
DEEGAN, R ;
NELSON, R ;
HE, HB ;
WOOD, M ;
WOOD, AJJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (03) :155-160
[7]   The Ile164 β2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure [J].
Liggett, SB ;
Wagoner, LE ;
Craft, LL ;
Hornung, RW ;
Hoit, BD ;
McIntosh, TC ;
Walsh, RA .
JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (08) :1534-1539
[8]   The effect of carvedilol on morbidity and mortality in patients with chronic heart failure [J].
Packer, M ;
Bristow, MR ;
Cohn, JN ;
Colucci, WS ;
Fowler, MB ;
Gilbert, EM ;
Shusterman, NH .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (21) :1349-1355
[9]   Racial profiling in medical research. [J].
Schwartz, RS .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (18) :1392-1393
[10]   Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes [J].
Takahashi, H ;
Kashima, T ;
Nomizo, Y ;
Muramoto, N ;
Shimizu, T ;
Nasu, K ;
Kubota, T ;
Kimura, S ;
Echizen, H .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 1998, 63 (05) :519-528