The goal of this study is to examine some of the many corrections and processing strategies that can have a significant influence on the ice mass change estimates computed from GRACE and ICESat mission data. These two missions, when combined, have the potential to generate new insights into the mass balance and geophysical processes of regions such as Antarctica, where such quantities are currently not well understood. Key to this combination is the identification of the major sources of uncertainty in the data processing. For the ICESat data, this includes an analysis into the calculation of the campaign biases, assumptions regarding the firn density, and a comparison between height rates derived from crossover and repeat track analysis. For the GRACE data, the focus will be on the impact of various GIA models and other a priori input values (i.e., C-20, geocenter motion, etc.). Comparisons with the latest data releases for both missions will be presented for the 4 year period spanning from October 2003 to October 2007. Recommendations for future work will also be discussed.