Poorly differentiated small cell carcinoma of the pancreas -: A case report and review of the literature

被引:11
作者
Berkel, S
Hummel, F
Gaa, J
Back, W
Hofheinz, R
Queisser, W
Singer, MV
Löhr, M
机构
[1] Heidelberg Univ, Mannheim Med Fac, Dept Med 2, Heidelberg, Germany
[2] Heidelberg Univ, Mannheim Med Fac, Inst Diagnost & Intervent Radiol, Heidelberg, Germany
[3] Heidelberg Univ, Mannheim Med Fac, Inst Pathol, Heidelberg, Germany
[4] Heidelberg Univ, Mannheim Med Fac, Oncol Outpatient Clin, Heidelberg, Germany
关键词
small cell carcinoma; pancreas; pancreatic carcinoma;
D O I
10.1159/000080526
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Small cell carcinoma (SCC) of the pancreas is a rare malignancy with an extremely poor prognosis. We present the case of a 74-year-old man with a 2-month history of upper abdominal discomfort who was diagnosed with SCC of the pancreas tail, involvement of peripancreatic and mesenteric lymph nodes and multiple liver metastases ( extended disease). A CT scan and a positive somatostatin receptor scintigraphy showed no evidence of a primary lung tumour. The diagnosis of a SCC was confirmed by biopsy. Local tumour control could be achieved by gemcitabine once a week and a long-acting somatostatin analogue once a month, but liver metastasis showed progress. Thus, 5-fluorouracil on a weekly basis was started. The patient died 8 months after diagnosis and had not been hospitalised in the meantime. Copyright (C) 2004 S. Karger AG, Basel and IAP.
引用
收藏
页码:521 / 526
页数:6
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