GnRH antagonists for treatment of polycystic ovarian syndrome

被引:21
作者
Cardone, VS [1 ]
机构
[1] Fertil Ctr New England, Reading, MA 01865 USA
关键词
ganirelix; GnRH antagonist; PCOS; treatment options;
D O I
10.1016/S0015-0282(03)00763-5
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To review treatment options for women with polycystic ovary syndrome (PCOS) seeking relief from infertility. Design: Review article and case studies. Results: Treatment options for women with PCOS include lifestyle modification, treatment with insulin-sensitizing agents, ovulation induction with clomiphene citrate (CC), FSH preparations, and possibly, GnRH antagonists. Conclusions: The GnRH antagonists provide a new treatment option for women with PCOS. When the goal is to restore normal ovulation, the use of GnRH antagonists is limited to the prevention of LH surges. When undertaking controlled ovarian hyperstimulation (COH) in women with PCOS, a GnRH antagonist protocol should be the protocol of choice. (C) 2003 by American Society for Reproductive Medicine.
引用
收藏
页码:S25 / S31
页数:7
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