Cirrhosis and Portal Hypertension in the Pediatric Population

被引：28

作者：

Chapin, Catherine A. ^{[1
]}

Bass, Lee M. ^{[1
]}

机构：

[1] Northwestern Univ, Ann & Robert H Lurie Childrens Hosp Chicago, Feinberg Sch Med, Div Pediat Gastroenterol Hepatol & Nutr, 225 East Chicago Ave,Box 65, Chicago, IL 60611 USA

来源：

CLINICS IN LIVER DISEASE | 2018年 / 22卷 / 04期

关键词：

Cirrhosis; Portal hypertension; Esophageal varices; Ascites; Biliary atresia; Children; SPONTANEOUS BACTERIAL PERITONITIS; SINGLE-CENTER EXPERIENCE; CHRONIC LIVER-DISEASE; RETROGRADE TRANSVENOUS OBLITERATION; INTRAHEPATIC PORTOSYSTEMIC SHUNTS; GASTRIC FUNDAL VARICES; V CONSENSUS WORKSHOP; BILIARY ATRESIA; ESOPHAGEAL-VARICES; PRIMARY PROPHYLAXIS;

D O I：

10.1016/j.cld.2018.06.007

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Cirrhosis is a complex process in which the architecture of the liver is replaced by structurally abnormal nodules due to cirrhosis. Cirrhosis frequently leads to the development of portal hypertension. In children, portal hypertension may have a wide range of causes, including extrahepatic portal vein obstruction, biliary atresia, alpha 1 antitrypsin deficiency, and autoimmune hepatitis. Gastroesophageal varices and ascites are two of the complications of portal hypertension likely to cause morbidity and mortality. This article also discusses extrahepatic manifestations of portal hypertension and treatment options.

引用

页码：735 / +

页数：20

共 93 条

[1]

Effect of erythromycin before endoscopy in patients presenting with variceal bleeding: a prospective, randomized, double-blind, placebo-controlled trial [J].