Particle size in the smoke produced by six different types of cigarette

被引:19
作者
Becquemin, M. H.
Bertholon, J. F.
Attoui, M.
Roy, F.
Roy, M.
Dautzenberg, B. [1 ]
机构
[1] Grp Hosp Pitie Salpetriere, Serv Pneumol, F-75651 Paris, France
[2] Univ Paris 07, Grp Hosp Pitie Salpetriere, APHP, Serv Cent Explorat Fonctionnelles Resp, F-2397 Paris, France
[3] Univ Paris 06, Hop St Antoine, APHP, Serv Physiol,UPRES 2397, Paris, France
[4] Univ Paris 12, UFR Sci, Dept Phys, Creteil, France
[5] Inst Radioprotect Surete Nucl, Fontenay Aux Roses, France
[6] Grp Hosp Pitie Salpetriere, Lab Granulometrie Depot Aerosols, F-75634 Paris, France
[7] Univ Paris 06, Grp Hosp Pitie Salpetriere, APHP, Serv Pneumol, Paris, France
关键词
tobacco smoke; aerosol particle sizing; lung deposition; HISTOLOGIC TYPE; LUNG-CANCER; DEPOSITION; TOBACCO; PARTICULATE; INHALATION; PATTERN;
D O I
10.1016/S0761-8425(07)91386-8
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Introduction For several decades a more peripheral distribution of the broncho-pulmonary pathologies related to tobacco has been observed. Methods The aim of this study is to examine whether changes in the particle size of cigarette smoke as the result of new manufacturing technologies could play a part in the observed epidemiologic changes through a more distal disposition of smoke particles in the airways. Using a smoking machine and a low pressure electrostatic impactor we measured the particle size of the smoke from six different types of cigarette, representing old and new manufacturing techniques. The effect of a filter was assessed by a size analyser measuring the electrical mobility of the particles. Results The results show a difference in particle size between the primary smoke inhaled by the smoker, S1 (0.27 +/- 0.03 microm.) and the secondary smoke, S2 inhaled by passive smokers (0.09 +/- 0.01 microm). There is no difference in particle size between the 6 different types of cigarette. Filters dilute the smoke without altering particle size. Conclusion The recent alterations in the distribution of tobacco related pathologies cannot be explained by changes in particle size in cigarette smoke. The explanation has to sought elsewhere.
引用
收藏
页码:845 / 852
页数:8
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