Effect of antibodies to morphine on synaptic plasticity of the hippocampus

被引：3

作者：

Beregovoi, NA ^{[1
]}

Pankova, TM ^{[1
]}

Sorokina, NS ^{[1
]}

Starostina, MV ^{[1
]}

机构：

[1] Russian Acad Med Sci, Siberian Div, Inst Mol Biol & Biophys, Novosibirsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2003年 / 135卷 / 02期

关键词：

morphine; antibodies; hippocampus; long-term posttetanic potentiation;

D O I：

10.1023/A:1023895109474

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Incubation of hippocampal slices with antibodies to morphine did not change the total excitatory postsynaptic potential of mossy fibers, but markedly facilitated long-term posttetanic potentiation. Culturing of the organotypic hippocampal culture in the presence of 10 muM morphine increased the total excitatory postsynaptic potential of mossy fibers and reduced the probability of long-term posttetanic potentiation.

引用

页码：114 / 116

页数：3

共 10 条

[1] BEREGOVOI NA, 1999, B SIB OTD ROS AKAD M, V91, P76
[2] BRIENDLE F, 1994, BRAIN RES B, V33, P17
[3] DERRICK BE, 1994, J NEUROSCI, V14, P4359
[4] Kalyuzhnyi L. V., 1998, Eksperimental'naya i Klinicheskaya Farmakologiya, V61, P21
[5] Kryzhanovskii G. N., 1997, NEUROIMMUNOPATHOLOGY
[6] Chronic in vivo morphine administration facilitates primed-bursts-induced long-term potentiation of Schaffer collateral-CA1 synapses in hippocampal slices in vitro
Mansouri, FA
Motamedi, F
Fathollahi, Y
[J]. BRAIN RESEARCH, 1999, 815 (02) : 419 - 423
[7] Augmentation of LTP induced by Primed-Bursts tetanic stimulation in hippocampal CA1 area of morphine dependent rats
Mansouri, FA
Motamedi, F
Fathollahi, Y
Atapour, N
Semnanian, S
[J]. BRAIN RESEARCH, 1997, 769 (01) : 119 - 124
[8] Tronnikov S I, 1992, Biull Eksp Biol Med, V114, P624
[9] VIKTOROV I V, 1975, Byulleten' Eksperimental'noi Biologii i Meditsiny, V80, P119
[10] XIE CW, 1991, J PHARMACOL EXP THER, V256, P289

← 1 →