Development of a novel assay method for colistin sulphomethate

被引:24
作者
Wootton, M [1 ]
Holt, HA [1 ]
MacGowan, AP [1 ]
机构
[1] Southmead Gen Hosp, N Bristol Healthcare Trust, Bristol Ctr Antimicrobial Res & Evaluat, Bristol BS 5NB, Avon, England
关键词
assay method; bioassay; colistin; cystic fibrosis; Pseudomonas aeruginosa;
D O I
10.1111/j.1469-0691.2005.01076.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Increased use of colistin therapy for infections caused by Pseudomonas aeruginosa has indicated a need for a more robust microbiological assay technique. This report describes a quick and simple microbiological assay for quantifying levels of colistin sulphomethate in serum and urine samples from cystic fibrosis patients. The technique uses no specialised or costly equipment and is suitable for use in all routine diagnostic microbiology laboratories.
引用
收藏
页码:243 / 244
页数:2
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