Origin of Aymaras from Bolivia and their relationship with other Amerindians according to HLA genes

被引：36

作者：

Arnaiz-Villena, A

Siles, N

Moscoso, J

Zamora, J

Serrano-Vela, JI

Gomez-Casado, E

Castro, MJ

Martinez-Laso, J

机构：

[1] Univ Complutense, Fac Med, Dept Immunol, E-28040 Madrid, Spain

[2] Hosp Mil, Div Lab, La Paz, Bolivia

来源：

TISSUE ANTIGENS | 2005年 / 65卷 / 04期

关键词：

Amerindians; Asians; Aymara; Eskimos; HLA; Na-Dene; Quechua;

D O I：

10.1111/j.1399-0039.2005.00356.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Aymara Amerindians from the Titicaca Lake Andean highlands are studied for HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1 gene frequencies. Genetic distances, neighbour-joining and correspondence analyses are performed by using other Amerindian and worldwide populations (15384 chromosomes are studied). The HLA genetic profile of Aymaras is different from neighbouring and language-related Quechuas (Incas). Both Quechuas and Aymaras seem to present an HLA-DRB1*0901 high frequency, which is present in a very low frequency or absent in Mesoamericans (Mazatecans, Mayans) and most studied Amerindians. Moreover, it is observed a closer relatedness of Aymaras with Amerindians from the Amazon Basin and Chaco lowlands, compared to Quechuans.

引用

页码：379 / 390

页数：12

共 52 条

[1] Molecular analysis of HLA-DRB1, DQA1, DQB1, DQ promoter polymorphism and extended class I/class II haplotypes in the Seri Indians from Northwest Mexico [J].

Alaez, C ;

Infante, E ;

Pujol, J ;

Duran, C ;

Navarro, JL ;

Gorodezky, C .

TISSUE ANTIGENS, 2002, 59 (05) :388-396

[2]

ALCINAFRANCH J, 1985, LOS ORIGENES AM

[3]

[Anonymous], 1959, INDIAN LINGUISTIC GR

[4]

[Anonymous], 2000, ARLEQUIN SOFTWARE PO

[5] The origin of Cretan populations as determined by characterization of HLA alleles [J].

Arnaiz-Villena, A ;

Iliakis, P ;

González-Hevilla, M ;

Longás, J ;

Gómez-Casado, E ;

Sfyridaki, K ;

Trapaga, J ;

Silvera-Redondo, C ;

Matsouka, C ;

Martínez-Laso, J .

TISSUE ANTIGENS, 1999, 53 (03) :213-226

[6] HLA genes in the chuvashian populationfrom European Russia: Admixture of central European and Mediterranean populations [J].

Arnaiz-Villena, A ;

Martinez-Laso, J ;

Moscoso, J ;

Livshits, G ;

Zamora, J ;

Gomez-Casado, E ;

Silvera-Redondo, C ;

Melvin, K ;

Crawford, MH .

HUMAN BIOLOGY, 2003, 75 (03) :375-392

[7] HLA genes in Macedonians and the sub-Saharan origin of the Greeks [J].

Arnaiz-Villena, A ;

Dimitroski, K ;

Pacho, A ;

Moscoso, J ;

Gómez-Casado, E ;

Silvera-Redondo, C ;

Varela, P ;

Blagoevska, M ;

Zdravkovska, V ;

Martínez-Laso, J .

TISSUE ANTIGENS, 2001, 57 (02) :118-127

[8] HLA genes in Mexican Mazatecans, the peopling of the Americas and the uniqueness of Amerindians [J].

Arnaiz-Villena, A ;

Vargas-Alarcón, G ;

Granados, J ;

Gómez-Casado, E ;

Longas, J ;

Gonzales-Hevilla, M ;

Zuñiga, J ;

Salgado, N ;

Hernández-Pacheco, G ;

Guillen, J ;

Martinez-Laso, J .

TISSUE ANTIGENS, 2000, 56 (05) :405-416

[9] Relatedness among Basques, Portuguese, Spaniards, and Algerians studied by HLA allelic frequencies and haplotypes [J].

ArnaizVillena, A ;

MartinezLaso, J ;

GomezCasado, E ;

DiazCampos, N ;

Santos, P ;

Martinho, A ;

BredaCoimbra, H .

IMMUNOGENETICS, 1997, 47 (01) :37-43

[10] PRIMARY IMMUNODEFICIENCY CAUSED BY MUTATIONS IN THE GENE ENCODING THE CD3-GAMMA SUBUNIT OF THE LYMPHOCYTE-T RECEPTOR [J].

ARNAIZVILLENA, A ;

TIMON, M ;

CORELL, A ;

PEREZACIEGO, P ;

MARTINVILLA, JM ;

REGUEIRO, JR .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (08) :529-533

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