Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis

被引:56
作者
McGovern, DPB
van Heel, DA
Negoro, K
Ahmad, T
Jewell, DP
机构
[1] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England
[2] Univ Oxford, Dept Gastroenterol, Oxford OX3 7BN, England
关键词
D O I
10.1086/379745
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:1465 / 1466
页数:2
相关论文
共 7 条
[1]   Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31 [J].
Armuzzi, A ;
Ahmad, T ;
Ling, KL ;
de Silva, A ;
Cullen, S ;
van Heel, D ;
Orchard, TR ;
Welsh, KI ;
Marshall, SE ;
Jewell, DP .
GUT, 2003, 52 (08) :1133-1139
[2]   Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan [J].
Bonen, DK ;
Ogura, Y ;
Nicolae, DL ;
Inohara, N ;
Saab, L ;
Tanabe, T ;
Chen, FF ;
Foster, SJ ;
Duerr, RH ;
Brant, SR ;
Cho, JH ;
Nuñez, G .
GASTROENTEROLOGY, 2003, 124 (01) :140-146
[3]   IBD5 is a general risk factor for inflammatory bowel disease: Replication of association with Crohn disease and identification of a novel association with ulcerative colitis [J].
Giallourakis, C ;
Stoll, M ;
Miller, K ;
Hampe, J ;
Lander, ES ;
Daly, MJ ;
Schreiber, S ;
Rioux, JD .
AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (01) :205-211
[4]   Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease [J].
Mirza, MM ;
Fisher, SA ;
King, K ;
Cuthbert, AP ;
Hampe, J ;
Sanderson, J ;
Mansfield, J ;
Donaldson, P ;
Macpherson, AJS ;
Forbes, A ;
Schreiber, S ;
Lewis, CM ;
Mathew, CG .
AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 72 (04) :1018-1022
[5]   Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease [J].
Negoro, K ;
McGovern, DPB ;
Kinouchi, Y ;
Takahashi, S ;
Lench, NJ ;
Shimosegawa, T ;
Carey, A ;
Cardon, LR ;
Jewell, DP ;
van Heel, DA .
GUT, 2003, 52 (04) :541-546
[6]   CARD15:: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis [J].
Rahman, P ;
Bartlett, S ;
Siannis, F ;
Pellett, FJ ;
Farewell, VT ;
Peddle, L ;
Schentag, CT ;
Alderdice, CA ;
Hamilton, S ;
Khraishi, M ;
Tobin, Y ;
Hefferton, D ;
Gladman, DD .
AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (03) :677-681
[7]   A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews [J].
Sugimura, K ;
Taylor, KD ;
Lin, YC ;
Hang, T ;
Wang, D ;
Tang, YM ;
Fischel-Ghodsian, N ;
Targan, SR ;
Rotter, JI ;
Yang, HY .
AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 72 (03) :509-518