Survival of Coxiella burnetii within free-living amoeba Acanthamoeba castellanii

被引:87
作者
La Scola, B [1 ]
Raoult, D [1 ]
机构
[1] Univ Mediterranee, Fac Med, Unite Rickettsies, UPRESA 6020, F-13385 Marseille 05, France
关键词
Coxiella burnetii; Acanthamoeba castellanii; amoeba;
D O I
10.1046/j.1469-0691.2001.00193.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Objective To determine whether Coxiella burnetii is able to survive within free-living ameoba. Methods When C. burnetii was co-cultured with the free-living amoeba species Acanthamoeba castellanii. Results Viable bacteria were detected for 18 days. Microscopic studies confirmed the presence of bacteria within vacuoles, some of which appeared to be spore-like forms. Conclusion These results indicate that free-living amoebae could provide an intracellular niche for the spore formation and survival of C. burnetii in the environment.
引用
收藏
页码:75 / 79
页数:5
相关论文
共 18 条
  • [1] Abu Kwaik Y, 1998, APPL ENVIRON MICROB, V64, P3127
  • [2] Obligate intracellular bacterial parasites of acanthamoebae related to Chlamydia spp.
    Amann, R
    Springer, N
    Schonhuber, W
    Ludwig, W
    Schmid, EN
    Muller, KD
    Michel, R
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1997, 63 (01) : 115 - 121
  • [3] Babudieri B., 1959, ADV VET SCI, V5, P82
  • [4] TROJAN-HORSES OF THE MICROBIAL WORLD - PROTOZOA AND THE SURVIVAL OF BACTERIAL PATHOGENS IN THE ENVIRONMENT
    BARKER, J
    BROWN, MRW
    [J]. MICROBIOLOGY-UK, 1994, 140 : 1253 - 1259
  • [5] Chlamydia-like obligate parasite of free-living amoebae
    Birtles, RJ
    Rowbotham, TJ
    Storey, C
    Marrie, TJ
    Raoult, D
    [J]. LANCET, 1997, 349 (9056) : 925 - 926
  • [6] Phylogenetic diversity of intra-amoebal legionellae as revealed by 16S rRNA gene sequence comparison
    Birtles, RJ
    Rowbotham, TJ
    Raoult, D
    Harrison, TG
    [J]. MICROBIOLOGY-UK, 1996, 142 : 3525 - 3530
  • [7] DIFFERENCES IN DESTRUCTION OF CYSTS OF PATHOGENIC AND NONPATHOGENIC NAEGLERIA AND ACANTHAMOEBA BY CHLORINE
    DEJONCKHEERE, J
    VANDEVOORDE, H
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1976, 31 (02) : 294 - 297
  • [8] PH-DEPENDENCE OF THE COXIELLA-BURNETII GLUTAMATE TRANSPORT-SYSTEM
    HACKSTADT, T
    WILLIAMS, JC
    [J]. JOURNAL OF BACTERIOLOGY, 1983, 154 (02) : 598 - 603
  • [9] La Scola B, 1999, LANCET, V353, P1330, DOI 10.1016/S0140-6736(99)00906-X
  • [10] PHAGOLYSOSOMAL ALKALINIZATION AND THE BACTERICIDAL EFFECT OF ANTIBIOTICS - THE COXIELLA-BURNETII PARADIGM
    MAURIN, M
    BENOLIEL, AM
    BONGRAND, P
    RAOULT, D
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1992, 166 (05) : 1097 - 1102