Fragmentation and reactions of two isomeric O-alkyl S-(2-dialkylamino)ethyl methylphosphonothiolates studied by electrospray ionization/ion trap mass spectrometry

被引:25
作者
Bell, AJ [1 ]
Murrell, J [1 ]
Timperley, CM [1 ]
Watts, P [1 ]
机构
[1] CB Syst, DERA, CBD Porton Down, Salisbury SP4 0JQ, Wilts, England
关键词
D O I
10.1016/S1044-0305(01)00274-4
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
An initial investigation into the electrospray ionization ion trap mass spectrometry (ESI/ITMS) of simple organophosphorus compounds [1] demonstrated that detailed structural information could be obtained by sequential fragmentation of the ions using collision induced dissociation (CID). Several novel fragmentations/rearrangements were observed and it was apparent that the full potential of this approach could not be exploited until a more detailed understanding of the ion fragmentations was obtained. Such an understanding will only result from a detailed study of a wide range of compounds. The present paper describes the investigation of two isomeric organophosphates of particular relevance to chemical warfare convention (CWC) considerations. (C) 2001 American Society for Mass Spectrometry.
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收藏
页码:902 / 910
页数:9
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