Vasculogenesis and angiogenesis in the IUGR placenta

被引：150

作者：

Arroyo, Juan A.

Winn, Virginia D.

机构：

[1] Univ Colorado, Dept Obstet & Gynecol, Div Maternal Fetal Med, Aurora, CO 80045 USA

[2] Univ Colorado, Dept Obstet & Gynecol, Div Reprod Biol, Aurora, CO 80045 USA

[3] Hlth Sci Ctr, Aurora, CO USA

来源：

SEMINARS IN PERINATOLOGY | 2008年 / 32卷 / 03期

关键词：

placenta; intrauterine growth restriction; vasculogenesis; angiogenesis;

D O I：

10.1053/j.semperi.2008.02.006

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Placenta vascular formation is important for fetal growth and development. Proper development of the placenta ensures the exchange of oxygen/nutrients and blood flow necessary for fetal growth. In this chapter, we will discuss the processes of vasculogenesis, angiogenesis, and pseudovasculogenesis during placental development and in pregnancies complicated by intrauterine growth restriction. Some of the factors controlling these processes include oxygen, the VEGF family of growth factors, and their receptors. Disruption in the balance of these controlling factors may explain the vascular malformations seen in pregnancies complicated by intrauterine growth restriction. © 2008 Elsevier Inc. All rights reserved.

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页码：172 / 177

页数：6

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