Host range of chlamydiaphages φCPAR39 and Chp3

被引：26

作者：

Everson, JS

Garner, SA

Lambden, PR

Fane, BA

Clarke, IN

机构：

[1] Univ Southampton, Southampton Gen Hosp, Sch Med, Southampton SO16 6YD, Hants, England

[2] Univ Arizona, Dept Vet Sci & Microbiol, Tucson, AZ 85721 USA

来源：

JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 21期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/JB.185.21.6490-6492.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The host range of phiCPAR39 is limited to four Chlamydophila species: C. abortus, C. caviae, C. pecorum, and C. pneumoniae. Chp3 (a newly discovered bacteriophage isolated from C. pecorum) shares three of these hosts (C. abortus, C. caviae, and C. pecorum) but can additionally infect Chlamydophila felis. The ability to support replication was directly correlated with the binding properties of the respective bacteriophages with their host species. Binding studies also show that phiCPAR39 and Chp3 use different host receptors to infect the same host cells: cell binding is sensitive to proteinase K treatment, confirming that the chlamydiaphage receptors are proteinaceous in nature.

引用

页码：6490 / 6492

页数：3

共 17 条

[1] Microviridae, a family divided:: Isolation, characterization, and genome sequence of φMH2K, a bacteriophage of the obligate intracellular parasitic bacterium Bdellovibrio bacteriovorus [J].