Cathepsin K inhibitors and antisclerostin antibodies. The next treatments for osteoporosis?

被引：7

作者：

Chapurlat, Roland ^{[1
,2
]}

机构：

[1] Univ Lyon, INSERM, UMR 1033, F-69437 Lyon, France

[2] Hop Edouard Herriot, Serv Rhumatol & Pathol Osseuse, 5 Pl Arsonval, F-69437 Lyon, France

来源：

JOINT BONE SPINE | 2016年 / 83卷 / 03期

关键词：

Osteoporosis; Romosozumab; Odanacatib; Cathepsin K; Antisclerostin; INCREASES BONE-FORMATION; POSTMENOPAUSAL WOMEN; SCLEROSTIN ANTIBODY; MINERAL DENSITY; ELDERLY-WOMEN; ODANACATIB; TURNOVER; FRACTURE; RISK; MASS;

D O I：

10.1016/j.jbspin.2015.09.008

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：254 / 256

页数：3

共 19 条

[1]

Mortality Risk Associated With Low-Trauma Osteoporotic Fracture and Subsequent Fracture in Men and Women [J].

Bliuc, Dana ;

Nguyen, D. Nguyen ;

Milch, Vivienne E. ;

Nguyen, Tuan V. ;

Eisman, John A. ;

Center, Jacqueline R. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 301 (05) :513-521

[2]

Compound Risk of High Mortality Following Osteoporotic Fracture and Refracture in Elderly Women and Men [J].

Bliuc, Dana ;

Nguyen, Nguyen D. ;

Nguyen, Tuan V. ;

Eisman, John A. ;

Center, Jacqueline R. .

JOURNAL OF BONE AND MINERAL RESEARCH, 2013, 28 (11) :2317-2324

[3]

Effects of Odanacatib on BMD and Safety in the Treatment of Osteoporosis in Postmenopausal Women Previously Treated With Alendronate: A Randomized Placebo-Controlled Trial [J].

Bonnick, Sydney ;

De Villiers, Tobias ;

Odio, Alberto ;

Palacios, Santiago ;

Chapurlat, Roland ;

DaSilva, Carolyn ;

Scott, Boyd B. ;

De Tilleghem, Celine Le Bailly ;

Leung, Albert T. ;

Gurner, Deborah .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2013, 98 (12) :4727-4735

[4]

Bone Density, Turnover, and Estimated Strength in Postmenopausal Women Treated With Odanacatib: A Randomized Trial [J].

Brixen, Kim ;

Chapurlat, Roland ;

Cheung, Angela M. ;

Keaveny, Tony M. ;

Fuerst, Thomas ;

Engelke, Klaus ;

Recker, Robert ;

Dardzinski, Bernard ;

Verbruggen, Nadia ;

Ather, Shabana ;

Rosenberg, Elizabeth ;

de Papp, Anne E. .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2013, 98 (02) :571-580

[5]

Incidence and risk factors for a second hip fracture in elderly women. The Study of Osteoporotic Fractures [J].

Chapurlat, RD ;

Bauer, DC ;

Nevitt, M ;

Stone, K ;

Cummings, SR .

OSTEOPOROSIS INTERNATIONAL, 2003, 14 (02) :130-136

[6]

Mechanisms of the anabolic effects of teriparatide on bone: Insight from the treatment of a patient with pycnodysostosis [J].

Chavassieux, Pascale ;

Karsdal, Morten Asser ;

Segovia-Silvestre, Toni ;

Neutzsky-Wulff, Anita V. ;

Chapurlat, Roland ;

Boivin, Georges ;

Delmas, Pierre D. .

JOURNAL OF BONE AND MINERAL RESEARCH, 2008, 23 (07) :1076-1083

[7]

Effects of Odanacatib on the Radius and Tibia of Postmenopausal Women: Improvements in Bone Geometry, Microarchitecture, and Estimated Bone Strength [J].

Cheung, Angela M. ;

Majumdar, Sharmila ;

Brixen, Kim ;

Chapurlat, Roland ;

Fuerst, Thomas ;

Engelke, Klaus ;

Dardzinski, Bernard ;

Cabal, Antonio ;

Verbruggen, Nadia ;

Ather, Shabana ;

Rosenberg, Elizabeth ;

de Papp, Anne E. .

JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 (08) :1786-1794

[8]

Duong Le T, 2012, Bonekey Rep, V1, P67, DOI 10.1038/bonekey.2012.67

[9]

Effect of ONO-5334 on Bone Mineral Density and Biochemical Markers of Bone Turnover in Postmenopausal Osteoporosis: 2-Year Results From the OCEAN Study [J].

Eastell, Richard ;

Nagase, Shinichi ;

Small, Maria ;

Boonen, Steven ;

Spector, Tim ;

Ohyama, Michiyo ;

Kuwayama, Tomohiro ;

Deacon, Steve .

JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 (02) :458-466

[10]

The Osteoporosis Treatment Gap [J].

Kanis, John A. ;

Svedbom, Axel ;

Harvey, Nicholas ;

McCloskey, Eugene V. .

JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 (09) :1926-1928

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