Effects of Fusarium moniliforme culture material containing known levels of fumonisin B1 on progress of Salmonella gallinarum infection in Japanese quail:: Clinical signs and hematologic studies

被引:14
作者
Deshmukh, S
Asrani, RK [1 ]
Jindal, N
Ledoux, DR
Rottinghaus, GE
Sharma, M
Singh, SP
机构
[1] Himachal Pradesh Agr Univ, Coll Vet & Anim Sci, Dept Vet Pathol, Palampur 176062, Himachal Prades, India
[2] Haryana Agr Univ, Coll Vet Sci, Dept Vet Epidemiol & Prevent Med, Hisar 125004, Haryana, India
[3] Univ Missouri, Fusarium Poultry Res Lab, Columbia, MO 65211 USA
[4] Himachal Pradesh Agr Univ, Coll Vet & Anim Sci, Dept Vet Microbiol, Palampur 176062, Himachal Prades, India
关键词
Fusarium moniliforme culture material; fumonisin B-1; Salmonella gallinarum; Japanese quail; hematology;
D O I
10.1637/7296-102804R
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
To study the individual and combined effects of fumonisin B-1 (FBI) toxicity and Salmonella serotype Gallinarum infection, Japanese quail (Coturnix coturnix japonica) were fed Fusarium moniliforme culture 4 material (2.5%), 150 mg FB1/kg ration, and were subsequently challenged orally with Salmonella Gallinarum organisms (2 X 10 colony-forming units) at 21 days of age. The chicks were fed culture material containing FBI from day 5 till the end of the experiment. After being infected with Salmonella Gallinarum, observations were made 1, 2, 3, 5, 7, 10, 14, and 21 days postinfection. The clinical signs of diarrhea with bloody discharges were more pronounced in the Salmonella-infected birds on the FBI diet. Mortality caused by Salmonella Gallinarum increased by 12% in the presence of FBI. Mean body weights in both the Salmonella-infected and FBI-fed groups were significantly lower than those of the controls at almost all intervals. Mean values of hemoglobin, packed cell volume, and total erythrocyte count were slightly higher in birds fed FBI but were lower in the Salmonella Gallinarum groups fed FBI and plain chick mash. Anemia was evident, between 5 and 10 days postinfection, in quail chicks infected with Salmonella Gallinarum alone. Total leukocyte counts were higher in Salmonella-infected and FBI-fed groups because of an increase in the number of heterophils and lymphocytes. However, the increase in lymphocyte response to infection was lower by 4.27%-30.09% between 3 and 21 days postinfection in the FB1-fed chicks compared with chicks infected with Salmonella Gallinarum. Alanine transaminase and total serum protein were slightly higher in both the infected and FBI-fed groups. This study revealed that the continuous presence of fumonisins in the diets of quail chicks might increase the susceptibility to or the severity of Salmonella Gallinarum infection.
引用
收藏
页码:274 / 280
页数:7
相关论文
共 49 条
[1]  
[Anonymous], 1994, VET LAB MED CLIN PAT
[2]   ANEMIA IN FOWL TYPHOID - IMMUNO-PATHOGENESIS AND ASSOCIATED PATTERNS OF ERYTHROCYTE DESTRUCTION [J].
ASSOKU, RKG ;
PENHALE, WJ .
JOURNAL OF COMPARATIVE PATHOLOGY, 1978, 88 (02) :219-236
[3]  
Benzamin M.M., 1985, OUTLINE VET CLIN PAT
[4]   The chronic effects of Fusarium moniliforme culture material, containing known levels of fumonisin B-1, in turkeys [J].
Bermudez, AJ ;
Ledoux, DR ;
Turk, JR ;
Rottinghaus, GE .
AVIAN DISEASES, 1996, 40 (01) :231-235
[5]   Effects of Fusarium moniliforme culture material containing known levels of fumonisin B-1 in ducklings [J].
Bermudez, AJ ;
Ledoux, DR ;
Rottinghaus, GE .
AVIAN DISEASES, 1995, 39 (04) :879-886
[6]  
Bhattacharya A, 2001, INDIAN J ANIM SCI, V71, P1034
[7]   VILLAGE CHICKENS AS A RESERVOIR OF SALMONELLA-PULLORUM AND SALMONELLA-GALLINARUM IN MOROCCO [J].
BOUZOUBAA, K ;
LEMAINGUER, K ;
BELL, JG .
PREVENTIVE VETERINARY MEDICINE, 1992, 12 (1-2) :95-100
[8]   FUMONISIN MYCOTOXICOSIS IN BROILERS - PERFORMANCE AND PATHOLOGY [J].
BROWN, TP ;
ROTTINGHAUS, GE ;
WILLIAMS, ME .
AVIAN DISEASES, 1992, 36 (02) :450-454
[9]  
BUXTON A, 1960, J Comp Pathol, V70, P308, DOI 10.1016/S0368-1742(60)80030-6
[10]  
CALNEK BW, 1994, DIS POULTRY